REFERENCES
1. MAVYRET [package insert]. North Chicago, IL: AbbVie Inc. 2. Data on file. AbbVie Inc. Source: Market Access Formulary Tracking Tool as of August 2023, and is subject to change. 3. Data on file. AbbVie Inc. IQVIA. National Prescription Audit (NPA), National Prescription Audit Market Dynamics (NPA MD) and Weekly Sales Perspective (WSP) and Longitudinal Prescription Claims (LRx) week ending 1/12/2018 to week ending 8/11/2023. August 2023. (IQVIA, all rights reserved). 4. Managed Markets Insight and Technology, LLCTM a trademark of MMIT, as of 11/9/2023.
GLOSSARY OF TERMS
AASLD = American Association for the Study of Liver Diseases
ALT = alanine aminotransferase
APRI = aspartate aminotransferase (AST) to platelet ratio index
ART = antiretroviral therapy
CC = compensated cirrhotic
CDC = Centers for Disease Control and Prevention
CKD = chronic kidney disease
CPSFU = core population with sufficient follow-up
Cure = sustained virologic response (SVR12); HCV RNA <LLOQ at 12 weeks after the end of treatment
DAA = direct-acting antiviral
DCV = daclatasvir
EC50 = 50% effective concentration
GT = genotype
HBV = hepatitis B virus
HCV = hepatitis C virus
HMG-CoA = hydroxymethylglutaryl coenzyme A
IDSA = Infectious Diseases Society of America
ITT = intent to treat
LLOQ = lower limit of quantification
MAT = medication-assisted treatment
mITT = modified intent to treat
NC = non-cirrhotic
NS = nonstructural protein
OTC = over the counter
PI = protease inhibitor
PPI = proton pump inhibitor
PrEP = pre-exposure prophylaxis
PRS-TE = prior treatment experience with regimens containing interferon, pegylated interferon, ribavirin, and/or sofosbuvir, but no prior treatment experience with an NS5A inhibitor or HCV NS3/4A protease inhibitor
PWID = people who inject drugs
RBV = ribavirin
Relapse = HCV RNA ≥LLOQ after end-of-treatment response among subjects who completed treatment
RT-PCR = reverse transcription polymerase chain reaction
SOF = sofosbuvir
SVR = sustained virologic response
SVR12 = sustained virologic response 12 weeks after the end of treatment
TE = treatment experienced
TN = treatment naïve
TW4 = treatment week 4